Preserving HHEAR's data legacy
The Human Health Exposure Analysis Resource (HHEAR) — and its predecessor CHEAR — established a national capability to measure environmental exposures across a diverse set of cohorts using standardized laboratory platforms and harmonized protocols.
This explorer is an independent effort to keep the HHEAR cohort catalog and its data searchable and analyzable. It indexes 54 cohorts and 240 chemical analytes, preserving original per-study data and metadata.
Data use & citation
Data originate from the HHEAR Data Repository (Icahn School of Medicine at Mount Sinai, IRB protocol 16-00947). Each dataset carries a DOI; please cite the originating study and the HHEAR program in any publication.
Methods
Analytics follow the HHEAR population-structure framework: censored-quantile-regression ExWAS, population-aware reference intervals within age- and sex-specific strata, within-class exposure correlations, and cumulative chemical exposure scores.
HHEAR is supported by the National Institute of Environmental Health Sciences (NIEHS). The original repository is operated at the Icahn School of Medicine at Mount Sinai.